12/20/2023. Our paper on neuron regeneration in zebrafish retinas is out on Nature communications. We showed that (1) different injury/damage models result in different regenerative outcomes with biased regeneration of lost neurons, and (2) regeneration process largely recapitulates retinal development.
12/16/2023. Welcome Dr. Sherine Awad to our team as a postdoctoral fellow.
11/1/2023. Our new preprinted paper led by Nguyet Le is now posted on BioRxiv. We have found a new way to efficiently reprogram retinal Muller glial cells into neurons, even in the absence of injury signal, by simultaneous inhibition of repressors.
06/07/23. Our paper on re-examining the role of Ptbp1 in reprograming astrocytes into neurons is out on Nature , Matters Arising. We showed that Ptbp1 deletion had little effect on astrocytes, and certainly did not reprogram astrocytes into neurons, in sharp contrast to previous claims. Our study calls for more stringent controls and criteria when studying cell fate conversion/reprograming.
06/05/23. Welcome Dr. Duc Vu to our team. We are glad to have you here. Dr. Vu obtained his PhD from Tokyo Institute of Technology, Japan. His postdoc research will focus on (1) cell fate engineering and (2) identification of neuronal circuits controlling different behaviors