44. Müller glia–mediated regeneration restores neuronal diversity and retinal circuit organization in the adult zebrafish | bioRxiv 2026

M. Nagashima^#, L. Santos, S. Awad, Z. Flickinger, P. F. Hitchcock^#, T. Hoang^#

43. Cigarette smoke and biological age induce degenerative heterogeneity in retinal pigment epithelium | PNAS 2026
K. Singh, Y. Jin, M.-W. Hu, I. Palazzo, M. Cano, T. Hoang, I. Bhutto, S. Wang, D. Sinha, S. Blackshaw, J. Qian, J. T. Handa

42. AAV-mediated generation of neurons in injury-induced and inherited retinal degenerations |bioRxiv 2025
M. Yang^#, S. Awad, A. Chung, J. Dang, M. Chong, Z. Flickinger, K.W. Wong, T. Hoang^#

41. Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Muller glia | eLife 2025
N. Le*, S. Awad*, I. Palazzo, T. Hoang, S. Blackshaw

40. Ptbp1 is not required for retinal neurogenesis and cell fate specification | eLife 2025
Haley Appel, Rogger P. Carmen-Orozco, Clayton P. Santiago, Thanh Hoang, Seth Blackshaw

39. Comparative single-cell multiomic analysis reveals evolutionarily conserved and species-specific cellular mechanisms mediating natural retinal aging | bioRxiv 2025

Pin Lyu, Isabella Palazzo, Yang jin, Leah Campbell, Clayton Santiago, Rogger Carmen-Orzoco, Thanh Hoang, Jared Tangeman, Alexander Park, Shawn Yang, Jianming Shao, Rui Chen, David Hyde, Jiang Qian, Seth Blackshaw

38. Robust reprogramming of glia into neurons by inhibition of Notch signaling and NFI factors in adult mammalian retina | Science Advances⋆⋆ 2024
N.Le, T.D.Vu, I.Palazzo,  R. Pulya, Y. Kim,  S. Blackshaw^#, T. Hoang^#

37. A large-scale CRISPR screen reveals context-specific genetic regulation of retinal ganglion cell regeneration | Development 2024
K. Emmerich, J. Hageter, T. Hoang, P. Lyu, A. V. Sharrock, A. Ceisel, J. Thierer, Z. Chunawala, S. Nimmagadda, I. Palazzo, F. Matthews, L. Zhang, D. T. White, C. Rodriquez, G. Graziano, P. Marcos, A. May, T. Mulligan, B. Reibman, M. T. Saxena, D. F. Ackerley, J. Qian, S. Blackshaw, E. Horstick, J. S. Mumm

36. A mutation-agnostic treatment for inherited retinal degenerations by drug repurposing | Nature Communication 2024
H. Leinonen, J. Zhang, L. Occelli, U. Seemab, E. Choi, L. Marinho, J. Querubin, A. Kolesnikov, T. Hoang, D. Lewandowski, T. Lee, E. Einstein, D. Einstein, Z. Dong, P. Kiser, S. Blackshaw, V.Kefalov, S.Petersen-Jones, K. Palczewski

35. miR-26 deficiency causes alterations in lens transcriptome and results in adult-onset cataract | Invest. Ophthalmol. Vis. Sci. 2024
A. Upreti, T. Hoang, M. Li, J. A. Tangeman, D. S. Dierker, B. D. Wagner, P. A. Tsonis, C. Liang, S. A. Lachke, M. L. Robinson

34. Ptbp1 deletion does not induce astrocyte-to-neuron conversion | Nature ** 2023
T. Hoang*^#, D. W. Kim*^#, H. Appel, M. Ozawa, S. Zheng, J. Kim, S. Blackshaw

33. Common and divergent gene regulatory networks control injury-induced and developmental neurogenesis in zebrafish retina | Nat. Communication ** 2023
P. Lyu, M. Iribarne, D. Serjanov, Y. Zhai, T. Hoang*, L. J. Campbell, P. Boyd, I. Palazzo, M. Nagashima, N. J. Silva, P. F. Hitchcock, J. Qian, D. R. Hyde, S. Blackshaw

32. Genetic loss of function of Ptbp1 does not induce glia-to-neuron conversion in retina | Cell Reports ** 2022
T. Hoang*^#, D. W. Kim*^#, H. Appel, N. A. Pannullo, P. Leavey, M. Ozawa, S. Zheng, M. Yu, N. S. Peachey, S. Blackshaw

31. Ectopic insert-dependent neuronal expression of GFAP promoter-driven AAV constructs in adult mouse retina | Front. Cell Dev. Biol. 2022
N. Le, H. Appel, N. Pannullo, T. Hoang, S. Blackshaw

30. Cell-specific cis-regulatory elements and mechanisms of non-coding genetic disease in human retina and retinal organoids | Dev. Cell 2022
E. D. Thomas, A. E. Timms, S. Giles, S. Harkins-Perry, P. Lyu, T. Hoang, J. Qian, V. E. Jackson, M. Bahlo, S. Blackshaw, M. Friedlander, K. Eade, T. J. Cherry

29. Quantitative transportomics identifies Kif5a as a major regulator of neurodegeneration | Elife 2022
S. H. Shah, L. M. Schiapparelli, Y. Ma, S. Yokota, M. Atkins, X. Xia, E. G. Cameron, T. Hoang, S. Saturday, C. B. Sun, C. Knasel, S. Blackshaw, J. R. Yates Iii, H. T. Cline, J. L. Goldberg

28. In vivo base editing rescues the function and survival of cone photoreceptors in a mouse model of early-onset inherited retinal degeneration | Nature Communications 2022
E. H. Choi , S. Suh, A. Foik, H. Leinonen, G. A. Newby, S. Banskota, T. Hoang, S. Du , X. D. Gao, Z. Dong, A. Raguram, S. Kohli, S. Blackshaw, D. C. Lyon, D. R Liu, K. Palczewski

27. NFkB-signaling promotes glial reactivity and suppresses Müller glia-mediated neuron regeneration in the mammalian retina | GLIA 2022
I. Palazzo, L. J. Todd, T. Hoang, T. A. Reh, S. Blackshaw, A. J. Fischer

26. Pantr2, a trans-acting lncRNA, modulates the differentiation potential of neural progenitors in vivo | BioRxiv 2022
J. Augustin, S. Takayangi, T. Hoang, B. Winer, S. Blackshaw, L. A Goff

25. Fatty acid-binding proteins and fatty acid synthase influence glial reactivity and promote the formation of Müller glia-derived progenitor cells in the chick retina | Development 2022
W. A. Campbell, A. Tangeman, H. M. El-Hodiri, E. C. Hawthorn, M. Hathoot, S. Blum, T. Hoang, S. Blackshaw, A. J. Fischer

24. Inhibition of ceramide accumulation in AdipoR1-/- mice increases photoreceptor survival and improves vision | JCI Insight 2022
D. Lewandowski, A. T. Foik, R. Smidak, E. H. Choi, J. Zhang, T. Hoang, A. Tworak, S. Suh, H. Leinonen, Z. Dong, A. F. Pinto, E. Tom, J. Luu, J. Lee, X. Ma, E. Bieberich, S. Blackshaw, A. Saghatelian, D. C. Lyon, D. Skowronska-Krawczyk, M. Tabaka, K. Palczewski

23. Gene regulatory networks controlling temporal patterning, neurogenesis, and cell fate specification in the mammalian retina | Cell Reports ** 2021
P. Lyu*, T. Hoang*, C. P. Santiago*, E. D. Thomas, A. E. Timms, H. Appel, M. Gimmen, N. Le, L. Jiang, D. W. Kim, S. Chen, D. Espinoza, A. E. Telger, K. Weir, B. S. Clark, T. J. Cherry, J. Qian, S. Blackshaw

22. Cannabinoid signaling promotes the de-differentiation and proliferation of Müller glia-derived progenitor cells | Glia 2021
W. A. Campbell, S. Blum, A. Reske, T. Hoang, S. Blackshaw, A. J. Fischer

21. Transcriptomic Profiling of Control and Thyroid-Associated Orbitopathy (TAO) Orbital Fat and TAO Orbital Fibroblasts Undergoing Adipogenesis | Invest. Ophthalmol. Vis. Sci. 2021
D. W. Kim, K. Taneja, T. Hoang, C. P. Santiago, T. J. McCulley, S. L. Merbs, N. R. Mahoney, S. Blackshaw, F. Rajaii

20. Midkine is neuroprotective and influences glial reactivity and the formation of Müller glia-derived progenitor cells in chick and mouse retinas | Glia 2021
W. A. Campbell, A. Fritsch-Kelleher, I. Palazzo, T. Hoang, S. Blackshaw, A. J. Fischer

19. Control of neurogenic competence in mammalian hypothalamic tanycytes | Sci. Adv. 2021
S. Yoo, J. Kim, P. Lyu, T. Hoang, A. Ma, V. Trinh, W. Dai, L. Jiang, P. Leavey, L. Duncan, J.-K. Won, S.-H. Park, J. Qian, S. P. Brown, S. Blackshaw

18. Gene regulatory networks controlling vertebrate retinal regeneration | Science ** 2020
T. Hoang*, J. Wang*, P. Boyd, F. Wang, C. Santiago, L. Jiang, S. Yoo, M. Lahne, L. J. Todd, M. Jia, C. Saez, C. Keuthan, I. Palazzo, N. Squires, W. A. Campbell, F. Rajaii, T. Parayil, V. Trinh, D. W. Kim, G. Wang, L. J. Campbell, J. Ash, A. J. Fischer, D. R. Hyde, J. Qian, S. Blackshaw

17. Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model | Hum. Mol. Genet. 2020
J. Luu, L. Kallestad, T. Hoang, D. Lewandowski, Z. Dong, S. Blackshaw, K. Palczewski

16. Single-Cell Analysis of Human Retina Identifies Evolutionarily Conserved and Species-Specific Mechanisms Controlling Development | Dev. Cell 2020
Y. Lu, F. Shiau, W. Yi, S. Lu, Q. Wu, J. D. Pearson, A. Kallman, S. Zhong, T. Hoang, Z. Zuo, F. Zhao, M. Zhang, N. Tsai, Y. Zhuo, S. He, J. Zhang, G. L. Stein-O’Brien, T. D. Sherman, X. Duan, E. J. Fertig, L. A. Goff, D. J. Zack, J. T. Handa, T. Xue, R. Bremner, S. Blackshaw, X. Wang, B. S. Clark

15. NF-κB signaling regulates the formation of proliferating Müller glia-derived progenitor cells in the avian retina | Development 2020
I. Palazzo, K. Deistler, T. Hoang, S. Blackshaw, A. J. Fischer

14. Photic generation of 11-cis-retinal in bovine retinal pigment epithelium | J. Biol. Chem. 2019
J. Zhang, E. H. Choi, A. Tworak, D. Salom, H. Leinonen, C. L. Sander, T. Hoang, J. T. Handa, S. Blackshaw, G. Palczewska, P. D. Kiser, K. Palczewski

13. Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification | Neuron 2019
B. S. Clark, G. L. Stein-O’Brien, F. Shiau, G. H. Cannon, E. Davis-Marcisak, T. Sherman, C. P. Santiago, T. Hoang, F. Rajaii, R. E. James-Esposito, R. M. Gronostajski, E. J. Fertig, L. A. Goff, S. Blackshaw

12. Matrix-metalloproteinase expression and gelatinase activity in the avian retina and their influence on Müller glia proliferation | Exp. Neurol. 2019
W. A. Campbell 4th, A. Deshmukh, S. Blum, L. Todd, N. Mendonca, J. Weist, J. Zent, T. Hoang, S. Blackshaw, J. Leight, A. J. Fischer

11. Reactive microglia and IL1β/IL-1R1-signaling mediate neuroprotection in excitotoxin-damaged mouse retina | J. Neuroinflammation 2019
L. Todd, I. Palazzo, L. Suarez, X. Liu, L. Volkov, T. Hoang, W. A. Campbell, S. Blackshaw, N. Quan, A. J. Fischer

10. Tanycyte-Independent Control of Hypothalamic Leptin Signaling | Front. Neurosci. 2019
S. Yoo, D. Cha, D. W. Kim, T. Hoang, S. Blackshaw

9. The selective estrogen receptor modulator raloxifene mitigates the effect of all-trans-retinal toxicity in photoreceptor degeneration | J. Biol. Chem. 2019
T. Getter, S. Suh, T. Hoang, J. T. Handa, Z. Dong, X. Ma, Y. Chen, S. Blackshaw, K. Palczewski

8. Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones | The FASEB. Journal 2019
P. D. Kiser, A. V. Kolesnikov, J. Z. Kiser, Z. Dong, B. Chaurasia, L. Wang, S. A. Summers, T. Hoang, S. Blackshaw, N. S. Peachey, V. J. Kefalov, A. K. Palczewski

7. Considerations for the use of Cre recombinase for conditional gene deletion in the mouse lens | Hum. Genomics 2019
P. T. Lam, S. L. Padula, T. Hoang, J. E. Poth, L. Liu, C. Liang, A. S. LeFever, L. M. Wallace, R. Ashery-Padan, P. K. Riggs, J. E. Shields, O. Shaham, S. Rowan, N. L. Brown, T. Glaser, M. L. Robinson

6. High-throughput transcriptome analysis reveals that the loss of Pten activates a novel NKX6-1/RASGRP1 regulatory module to rescue microphthalmia caused by Fgfr2-deficient lenses | Hum. Genet. 2019
S. L. Padula, D. Anand, T. Hoang, B. R. Chaffee, L. Liu, C. Liang, S. A. Lachke, M. L. Robinson

5. ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration | Nat. Commun. 2019
. Wang, C. Zibetti, P. Shang, S. R. Sripathi, P. Zhang, M. Cano, T. Hoang, S. Xia, H. Ji, S. L. Merbs, D. J. Zack, J. T. Handa, D. Sinha, S. Blackshaw, J. Qian

4. Lens development requires DNMT1 but takes place normally in the absence of both DNMT3A and DNMT3B activity | Epigenetics 2016
T. Hoang*, E. R. Horowitz*, B. R. Chaffee, P. Qi, R. E. Flake, D. G. Bruney, B. J. Rasor, S. E. Rosalez, B. D. Wagner, M. L. Robinson

3. FGFR and PTEN signaling interact during lens development to regulate cell survival | Dev. Biol. 2016
B. R. Chaffee*, T. Hoang*, M. R. Leonard, D. G. Bruney, B. D. Wagner, J. R. Dowd, G. Leone, M. C. Ostrowski, M. L. Robinson

2. CADBURE: A generic tool to evaluate the performance of spliced aligners on RNA-Seq data | Sci. Rep. 2015
P. K. R. Kumar*, T. Hoang*, M. L. Robinson, P. A. Tsonis, C. Liang

1. Comparative transcriptome analysis of epithelial and fiber cells in newborn mouse lenses with RNA sequencing | Mol. Vis. 2014
T. Hoang*, P. K. R. Kumar*, S. Sutharzan, P. A. Tsonis, C. Liang, M. L. Robinson